Search results for "Olfactory Transduction Pathway"

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Postnatal odorant exposure induces peripheral olfactory plasticity at the cellular level

2014

Mammalian olfactory sensory neurons (OSNs) form the primary elements of the olfactory system. Inserted in the olfactory mucosa lining of the nasal cavity, they are exposed to the environment and their lifespan is brief. Several reports say that OSNs are regularly regenerated during the entire life and that odorant environment affects the olfactory epithelium. However, little is known about the impact of the odorant environment on OSNs at the cellular level and more precisely in the context of early postnatal olfactory exposure. Here we exposed MOR23-green fluorescent protein (GFP) and M71-GFP mice to lyral or acetophenone, ligands for MOR23 or M71, respectively. Daily postnatal exposure to …

Olfactory systemPatch-Clamp TechniquessourisReceptors Odorant[ SDV.BA ] Life Sciences [q-bio]/Animal biologybiologie neurosensorielleMembrane Potentials0302 clinical medicinemolecular biology[SDV.BDD]Life Sciences [q-bio]/Development BiologydéveloppementAnimal biology0303 health scienceseducation.field_of_studyNeuronal PlasticityGeneral Neuroscience[SDV.BA]Life Sciences [q-bio]/Animal biologyBiologie du développementArticlesOlfactory BulbDevelopment BiologySmellmedicine.anatomical_structureélectrophysiologie[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]development;développement;electrophysiology;électrophysiologie;mice;souris;molecular biology;biologie moléculaire;olfaction;plasticity;plasticiténeurone récepteur olfactifolfactionmiceGreen Fluorescent ProteinsPopulationMice Transgenicneurone olfactifSensory systemOlfactionBiologybiologie moléculaireOlfactory Receptor Neurons03 medical and health sciencesOlfactory mucosaBiologie animalemedicineAnimalsOlfactory Transduction Pathway[ SDV.BDD ] Life Sciences [q-bio]/Development Biologyeducationdevelopment030304 developmental biologyOlfactory receptorplasticitéNeuroscienceselectrophysiologyElectrooculographyAnimals NewbornGene Expression RegulationNeurons and Cognitionplasticity[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]OdorantsNeuroscienceOlfactory epithelium030217 neurology & neurosurgery

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